Benzofuran derivative

The present invention is directed to a compound represented by formula (1): (wherein R represents an alkyl group which may have a substituent or an alkenyl group which may have a substituent; and each of R and R represents a hydrogen atom, an alkyl group, a hydroxyalkyl group, a dihydroxyalkyl group...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser:	SATO SEIICHI,KOSHI TOMOYUKI,MIZOGUCHI TOSHIMI,YASUOKA KYOKO,KUMAI NATSUYO,TOTSUKA JUNKO,TAMURA MASAHIRO,OHKUCHI MASAO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to a compound represented by formula (1): (wherein R represents an alkyl group which may have a substituent or an alkenyl group which may have a substituent; and each of R and R represents a hydrogen atom, an alkyl group, a hydroxyalkyl group, a dihydroxyalkyl group, or an alkynyl group, or R and R form, together with the nitrogen atom adjacent thereto, a nitrogen-containing saturated heterocyclic group which may have a substituent) and a drug composition containing the compound. The compound exhibits tumor necrosis factor (TNF- alpha ) production inhibitory effect and improved absorption upon oral administration.