Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same

The present invention relates to an isothiazole derivative of the following formula 1 or nontoxic salt thereof: wherein, R1 is hydrogen, alkoxy group or halogen group; R2 is methyl or amino group. According to the present invention, isothiazole derivative or nontoxic salt thereof having antipyretic,...

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1. Verfasser: CHO II HWAN,KO DONG HYUN,CHAE MYEONG YUN,MIN IN KI,KIM YOUNG HOON,CHUNG YOUNG MEE,PARK HYUN JUNG,NOH JI YOUNG,KIM II HWAN,RYU HYUNG CHUL,PARK SANG WOOK,JUNG SUNG HAK,KIM JONG HOON
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Sprache:eng
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Zusammenfassung:The present invention relates to an isothiazole derivative of the following formula 1 or nontoxic salt thereof: wherein, R1 is hydrogen, alkoxy group or halogen group; R2 is methyl or amino group. According to the present invention, isothiazole derivative or nontoxic salt thereof having antipyretic, analgesic and antiphlogistic activity and an improved side effect; process for the preparation thereof; and pharmaceutical composition including the same can be provided.