HBsAg fusion gene with carboxyl-end containing pre S2 immune determinant and protein thereof

The invention relates to the genes and proteins encoding novel hepatitis B virus surface antigen, wherein the pro-S2 antigen (Metl-Gly26) coded sequence of the hepatitis B virus and having B cell and T cell and polymeried albumin receptor binding site is fused onto the end of the main protein (S) ge...

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Bibliographische Detailangaben
1. Verfasser:	CHANGYAO,JIANG TAN
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to the genes and proteins encoding novel hepatitis B virus surface antigen, wherein the pro-S2 antigen (Metl-Gly26) coded sequence of the hepatitis B virus and having B cell and T cell and polymeried albumin receptor binding site is fused onto the end of the main protein (S) gene and expressed in a yeast system, the expression product has both S and preS2 antigen property, and can be assembled into virus sample particles with a diameter of 20-35 nm.