Process for preparing insulin compounds

A preferred way of converting insulin precursors into insulin compounds is to perform an enzymatic peptide cleavage in an aqueous medium and, thereafter, without removal of the intermediate product formed, to add an amino acid ester or a peptide ester and an organic solvent so that the desired coupl...

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Bibliographische Detailangaben
Hauptverfasser: BOGSNES ARE, BALSCHMIDT PER, CHRISTIANSEN INGUN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A preferred way of converting insulin precursors into insulin compounds is to perform an enzymatic peptide cleavage in an aqueous medium and, thereafter, without removal of the intermediate product formed, to add an amino acid ester or a peptide ester and an organic solvent so that the desired coupling takes place.