Orally disintegrating tablet of corydalis rhizome and its preparation

The orally disintegrating decumbent corydalis tablet of the present invention includes total decumbent corydalis alkaloid in 1-20 weight portions, stuffing 100-300 weight portions, disintegrating agent 5-100 weight portions, flow assistant 1-10 weight portions and corrective 0.5-5 weight portions. It is prepared through direct tabletting and spray drying process. The orally disintegrating decumbent corydalis tablet of the present invention is superior to available orally taken decumbent corydalis preparation, and has raised bioavailability. Its taking needs no drinking water and it may be disintegrated fast with saliva only, so that it may be taken conveniently. 本发明公开了一种夏天无口腔崩解片及其制备方法，本发明的夏天无口腔崩解片，其中包括有效治疗量的夏天无总碱和可促使制剂在口腔内迅速崩解释放药物的药用辅料，药用辅料包括填充剂、崩解剂、助流剂、矫味剂。夏天无总碱用量为1-20重量份数，填充剂用量为100-300重量份数，崩解剂用量为5-100重量份数，助流剂用量为1-10重量份数，矫味剂用量为0.5-5重量份数。本发明选用了直接压片工艺和喷雾干燥工艺。本发明的夏天无口腔崩解片克服了夏天无现有口服制剂的缺点，提高了生物利用度，不需用水送服，在口腔内遇到唾液就能够迅速溶解，服用方便，给一些吞服功能不好、婴幼儿及儿童、取水不便的患者提供了便利。