Novel 2H -pyridazine-3-one derivatives, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient

本发明涉及新颖的式I 2H-哒嗪-3-酮衍生物、含有它们的药物组合物和该活性成分的制备方法。这些新颖的化合物具有神经抑制效果,主要能够用于治疗精神分裂症。式I中,R代表氢原子或C#-[1-4]烷基,X和Y独立地代表氢原子、卤原子或式II基团,其条件是X和Y之一总是表示式II基团,则另一个代表氢原子或卤原子,其中在式II中,n具有1或2的数值。 The invention refers to novel 2H-pyridazine-3-one derivatives of the formula I, pharmaceutical compositions containing the same...

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1. Verfasser: MIKLOSNE KOVACS ANIKO,RACZNE BAJNOGEL JUDIT,LEVAY GYOERGY
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:本发明涉及新颖的式I 2H-哒嗪-3-酮衍生物、含有它们的药物组合物和该活性成分的制备方法。这些新颖的化合物具有神经抑制效果,主要能够用于治疗精神分裂症。式I中,R代表氢原子或C#-[1-4]烷基,X和Y独立地代表氢原子、卤原子或式II基团,其条件是X和Y之一总是表示式II基团,则另一个代表氢原子或卤原子,其中在式II中,n具有1或2的数值。 The invention refers to novel 2H-pyridazine-3-one derivatives of the formula I, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient. The novel compounds possess neuroleptic effect and can be used, primarily, for the treatment of schizophrenia. In formula I, R stands for a hydrogen atom or a C1-4, alkyl group, X and Y represent, independently, a hydrogen atom, a halogen atom or a group of the formula II, with the proviso that one of X and Y means always a group of the formula II, and then the other one stands for a hydrogen atom or a halogen atom, wherein in formula II n has a value of 1 or 2.