N-hydroxymethyl isothiazolinone preparation method

A process for preparing N-methylol isothiazolinone comprises reacting N-butoxy methacrylamide with sodium polysulfide, creating 2 (N-butoxymethacrylic acid acidamide) disulfide, which is being subjected to reaction with sulfuric chloride to obtain N-methylol isothiazolinone, the reaction between N-butoxy methacrylamide and sodium polysulfide being carried in water and the solution of ethanol or methanol, the weight ratio of water and methanol or ethanol or propanol or butanol is 1:0.01-2. 一种N-羟甲基异噻唑啉酮的制备方法，其特征是使N-丁氧基甲基丙烯酰胺与多硫化钠进行反应生成二硫代二(N-丁氧基甲基丙烯酸酰胺)，后者再与硫酰氯反应生成N-羟甲基异噻唑啉酮。所述的N-丁氧基甲基丙烯酰胺与多硫化钠的反应在水和乙醇或甲醇的溶液中进行，所述的水和甲醇或乙醇或丙醇或丁醇的重量比为1∶0.01-2。本发明的优点是原料N-丁氧基甲基丙烯酰胺易得，反应步骤少、产率高、成本低。