4-amino-5-phenyl-7-cyclobutyl-pyrrolo (2,3-D) pyrimidie derivatives

本发明涉及新的4-氨基-5-苯基-7-环丁基-吡咯并[2，3-d]嘧啶衍生物；其制备方法；其在治疗人或动物的方法中的应用；其单独或与一种或多种其它药学活性化合物在治疗疾病中的用途，特别是增殖性疾病如肿瘤；治疗哺乳动物特别是人类的该类疾病的方法；以及所述化合物单独或与一种或多种其它药学活性化合物在制备用于尤其是治疗增殖性疾病如肿瘤的药物组合物(药物)中的用途。 The invention relates to new 4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives, processes for the preparation thereof, the application thereof in a process for the treatment of the human or animal body, the use thereof-alone or in combination with one or more other pharmaceutically active compounds-for the treatment of a disease, especially a proliferative disease, such as a tumour disease, a method for the treatment of such diseases in mammals, especially in humans, and the use of such a compound-alone or in combination with one or more other pharmaceutically active compounds-for the preparation of a pharmaceutical composition (medicament) for the treatment especially of a proliferative disease, such as a tumour.