Blood purifying apparatus

提供除去低分子蛋白质等血液处理能力强,而且由透析液侧流入内毒素少的血液净化器。本发明的血液净化器,使通过高分子物质侵入试验得到的侵入率达到10%以下,可以制得性能高,而且内毒素实质上不会侵入的血液净化器。本发明的血液净化器,以低分子蛋白质的清除率等为代表的血液净化性能高,而且内毒素实质上不会从透析液侧侵入,因此对于肾功能低下的患者的治疗是有用的。 A blood purifying apparatus having excellent purification performance (elimination of low molecular proteins, etc.) and being...

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Bibliographische Detailangaben
1. Verfasser: UEZUMI SATOSHI,YOSHIDA MAKOTO
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:提供除去低分子蛋白质等血液处理能力强,而且由透析液侧流入内毒素少的血液净化器。本发明的血液净化器,使通过高分子物质侵入试验得到的侵入率达到10%以下,可以制得性能高,而且内毒素实质上不会侵入的血液净化器。本发明的血液净化器,以低分子蛋白质的清除率等为代表的血液净化性能高,而且内毒素实质上不会从透析液侧侵入,因此对于肾功能低下的患者的治疗是有用的。 A blood purifying apparatus having excellent purification performance (elimination of low molecular proteins, etc.) and being contaminated with little endotoxins flowing from the dialyzate side. Attention was paid to the solute permeability coefficient alpha and water permeability performance Lp of blood purifying apparatus and the relation between alpha and Lp has been examined. As a result, a blood purifying apparatus having excellent purification performance and substantially being free from invasion of endotoxins was obtained by regulating the value alpha /Lp to 6x10 or above, or regulating alpha within a range of 8x10 to 1.5x10, and the value alpha x Lp to 2.4x10 or less. Also, a blood purifying apparatus having excellent purification performance and substantially being free from invasion of endotoxins was obtained by regulating the invasion ratio which is obtained by the polymer invasion test to 10% or less. The blood purifying apparatus has an excellent blood purifying performance expressed typically by the elimination ratio of low-molecular weight proteins and is substantially free from invasion of endotoxins from the dialyzate side, which makes it useful in, for example, treating patients with renal dysfunction.