Earthworm freeze dried powder injection and preparation method

The present invention is freeze dried earthworm powder for injection for treating cardiac vascular diseases and its making process. The product of the present invention contains earthworm fibrillarin extractive, of which each milligram contains earthworm kinase with cellulolytic acitivity 80000-120000 unit and which, SDS polyacrylamide gel electrophoresis process shows, includes component with molecular weight over 30 KD over 50 % and component with molecular weight over 23 KD over 90 %. The product has obvious cellulolytic effect to both newly formed thrombus and old thrombus, no allergic reaction and no heat source. 注射用地龙冻干粉针剂及其制作方法，一种注射用的地龙冻干粉针剂及其制作方法。心血管疾病常需要使用溶栓药物来治疗，来常常使用尿激酶等，使用过程中，经常出现出血和并症，对新形成血栓有抑制作用，对陈旧血栓作用很差。本产品的组成包括：地龙纤维蛋白的提取物，所述的地龙提取物中每毫克含有溶纤活性的蚓激酶8-12万单位，以SDS聚丙烯酰胺凝胶电泳方法鉴定时，其中分子量3万以上的50％，分子量2.3万以上的占90％。本发明的工艺制作的产品具有明显的溶纤效果，无过敏反应、无热源，对于新形成血栓和陈旧血栓具有明显的溶纤效果。