Nicotine-containing film preparation

三层结构的薄膜制剂,所述薄膜制剂包括:含尼古丁层,所述含尼古丁层在施加于Bakelite板上时具有1g-30g/20mm的180度剥离强度,在水中具有3分钟-10分钟的溶解度,并且包含尼古丁和可食用水溶性聚合物;和分别层压在含尼古丁层两面上的两个包衣层,所述包衣层在施加于Bakelite板上时分别具有100g-500g/20mm的180度剥离强度,在水中具有0.5-3分钟的溶解度,并且包含水溶性且不吸收水的多糖和/或可食用聚合物以及软化剂。 A film preparation of a three-layer structure which comprises: a nicotine-con...

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Hauptverfasser: SAWAI YOSHIHIRO, AWAMURA TSUTOMU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:三层结构的薄膜制剂,所述薄膜制剂包括:含尼古丁层,所述含尼古丁层在施加于Bakelite板上时具有1g-30g/20mm的180度剥离强度,在水中具有3分钟-10分钟的溶解度,并且包含尼古丁和可食用水溶性聚合物;和分别层压在含尼古丁层两面上的两个包衣层,所述包衣层在施加于Bakelite板上时分别具有100g-500g/20mm的180度剥离强度,在水中具有0.5-3分钟的溶解度,并且包含水溶性且不吸收水的多糖和/或可食用聚合物以及软化剂。 A film preparation of a three-layer structure which comprises: a nicotine-containing layer comprising nicotine and an edible water-soluble polymer and having a 180-degree peel strength in application to a Bakelite plate of 1 g to 30 g/20 mm and a solubility in water of 3 minutes to 10 minutes, and two coating layers laminated respectively on both sides of the nicotine-containing layer, the coating layers comprising a water-soluble and non-water-absorbing polysaccharide and/or an edible polymer and a softener and the coating layers each having a 180-degree peel strength in application to a Bakelite plate of 100 g to 500 g/20 mm and a solubility in water of 0.5 minutes to 3 minutes.