Gclq receptor, HIV-laplzo area jointed with same and relative peptide and target-directional antibody

本发明公开了基于gC1q-R上结合HIV-1 gp120的结合位点的免疫原和肽，以及基于HIV-1 gp120上结合gC1q-R的结合位点的免疫原和肽。gC1q-R上的结合gp120的结合位点的序列如SEQ ID NO：2所示，HIV-1 gp120上结合gC1q-R的结合位点的序列如SEQ ID NO：3所示。还公开了针对所有这些免疫原和肽的抗体和结合分子，以及诱导这种抗体的内源生产。 Disclosed are immunogens and peptides based on the binding site of gC1q-R for HIV-1 gp120, and immunogen...

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Bibliographische Detailangaben
Hauptverfasser:	MICKER S.C. PHONE, SYCILI R.Y. SON, BEER N.C. SUNG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	本发明公开了基于gC1q-R上结合HIV-1 gp120的结合位点的免疫原和肽，以及基于HIV-1 gp120上结合gC1q-R的结合位点的免疫原和肽。gC1q-R上的结合gp120的结合位点的序列如SEQ ID NO：2所示，HIV-1 gp120上结合gC1q-R的结合位点的序列如SEQ ID NO：3所示。还公开了针对所有这些免疫原和肽的抗体和结合分子，以及诱导这种抗体的内源生产。 Disclosed are immunogens and peptides based on the binding site of gC1q-R for HIV-1 gp120, and immunogens and peptides based on the binding site of HIV-1 gp120 for gC1q-R. The sequence of the gC1q-R binding site for gp120 is shown in SEQ ID NO.: 2. The sequence of the HIV-1 gp120 binding site for gC1q-R is shown in SEQ ID NO.: 3. Also disclosed are antibodies and binding molecules to all such immunogens and peptides, and inducing the endogenous production of such antibodies.