Novel aminopeptidase and its gene

本发明的目的是：提供来源于曲菌的可有效分解难分解的肽氨肽酶，以及编码该氨肽酶的基因。本发明提供来源于构巢曲霉的氨肽酶及编码该酶的核酸分子。本发明特别提供：具有序列表SEQ ID NO：2氨基酸编号1～519表示的氨基酸序列的蛋白质；或由在该氨基酸序列中包含1个或多个氨基酸置换、缺失、插入、添加或倒位的氨基酸序列构成，且具有催化从肽的N末端释放氨基酸的反应的活性的蛋白质；以及编码上述蛋白质的核酸分子。 The object of the present invention is to provide Koji mold aminopeptidases capable of efficiently...

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Bibliographische Detailangaben
Hauptverfasser:	NINOMIYA DAIKI, KOIBUCHI KYOKO, KOJIMA MARI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	本发明的目的是：提供来源于曲菌的可有效分解难分解的肽氨肽酶，以及编码该氨肽酶的基因。本发明提供来源于构巢曲霉的氨肽酶及编码该酶的核酸分子。本发明特别提供：具有序列表SEQ ID NO：2氨基酸编号1～519表示的氨基酸序列的蛋白质；或由在该氨基酸序列中包含1个或多个氨基酸置换、缺失、插入、添加或倒位的氨基酸序列构成，且具有催化从肽的N末端释放氨基酸的反应的活性的蛋白质；以及编码上述蛋白质的核酸分子。 The object of the present invention is to provide Koji mold aminopeptidases capable of efficiently hydrolyzing persistent peptides and also genes encoding the aminopeptidases. The present invention provides Aspergillus nidulans aminopeptidase and nucleic acid molecules encoding it. In particular, the present invention provides a protein having an amino acid sequence represented by amino acid Nos. 1 to 519 in SEQ ID NO: 2, or a protein containing the substitution, deletion, insertion, addition or inversion of one or more amino acids in said sequence, and which protein has an activity of catalyzing the reaction for releasing an amino acid at an N-terminal of a peptide, and nucleic acid molecules encoding them.