Cyclic nitrones and pharmaceutical compositions containing them

本发明涉及新的环状硝酮类化合物及其在预防由自由基所引起的氧化性组织损伤中的用途、它们治疗多种疾病的用途，在所述疾病中自由基通过氧化作用引起组织损伤或破坏，此外本发明还涉及含有这些环状硝酮类化合物的药物组合物。 The present invention is directed to novel cyclic nitrones and their use in the prevention of oxidation tissue damage by free radicals, their use in the treatment of a number of disease states in...

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Bibliographische Detailangaben
Hauptverfasser:	BOWEN STEPHEN M, THOMAS CRAIG E, FEVIG THOMAS L
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	本发明涉及新的环状硝酮类化合物及其在预防由自由基所引起的氧化性组织损伤中的用途、它们治疗多种疾病的用途，在所述疾病中自由基通过氧化作用引起组织损伤或破坏，此外本发明还涉及含有这些环状硝酮类化合物的药物组合物。 The present invention is directed to novel cyclic nitrones and their use in the prevention of oxidation tissue damage by free radicals, their use in the treatment of a number of disease states in which radicals either damage or destroy tissues via oxidation, and pharmaceutical compositions containing these cyclic nitrones.