Medicament form of tatin class
A dried suspension of tatin medicines is prepared from the active component chosen from lovastatin, simvastatin, pravastatin, etc and the carrier containing diluent or disperser, suspending aid, antioxidizing agent, chelating agent, flowing aid, flavouring and color correcting agent through proporti...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | A dried suspension of tatin medicines is prepared from the active component chosen from lovastatin, simvastatin, pravastatin, etc and the carrier containing diluent or disperser, suspending aid, antioxidizing agent, chelating agent, flowing aid, flavouring and color correcting agent through proportionally mixing, granulating or pulverizing, and sieving. Its advantage is high solubility.
本发明涉及他汀类药物的新剂型,是一种用他汀类药物加载体制成的干混悬剂。公开的他汀类药物为洛伐他汀、辛伐他汀、普伐他汀、阿托伐他汀、氟伐他汀以及以他汀类药物为主的复方制剂;公开的新制剂载体包括稀释剂或分散剂、助悬剂、抗氧剂、螯合剂、助流剂、矫味剂、矫色剂等;公开的制备方法是主药与载体采用适宜的方法混匀制成颗粒或制成粉末后过筛分装即得。经过分散、矫味等工艺,制剂具有服用方便、药物溶出度快等优点。 |
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