New spirotricyclic derivatives and their use as phosphodiesterase-7-inhibitors
本发明提供了属于PDE7抑制剂的具有下列通式(I)、(II)和(III)的化合物及其制备方法及其在治疗与采用PDE7抑制剂的疗法相关的疾病中的应用，其中X#-[1]、X#-[2]、X#-[3]、X#-[4]、X、Y、Z、A和Z#+[1]如本说明书中所定义。 The invention provides compounds which are PDE7 inhibitors, having the following formula (I), (II) and (III), in which X 1 , X 2 , X 3 , X 4 , X, Y, Z, A and Z 1 are as de...
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| creator | P. BERNARDELLI P. DUCROT E. LORTHIOIS |
| description | 本发明提供了属于PDE7抑制剂的具有下列通式(I)、(II)和(III)的化合物及其制备方法及其在治疗与采用PDE7抑制剂的疗法相关的疾病中的应用，其中X#-[1]、X#-[2]、X#-[3]、X#-[4]、X、Y、Z、A和Z#+[1]如本说明书中所定义。
The invention provides compounds which are PDE7 inhibitors, having the following formula (I), (II) and (III), in which X 1 , X 2 , X 3 , X 4 , X, Y, Z, A and Z 1 are as defined in the description, methods for preparing them and their use for the treatment of disorders for which therapy by a PDE7 inhibitor is relevant. |
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The invention provides compounds which are PDE7 inhibitors, having the following formula (I), (II) and (III), in which X 1 , X 2 , X 3 , X 4 , X, Y, Z, A and Z 1 are as defined in the description, methods for preparing them and their use for the treatment of disorders for which therapy by a PDE7 inhibitor is relevant.</description><edition>7</edition><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040519&DB=EPODOC&CC=CN&NR=1498212A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040519&DB=EPODOC&CC=CN&NR=1498212A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>P. BERNARDELLI</creatorcontrib><creatorcontrib>P. DUCROT</creatorcontrib><creatorcontrib>E. LORTHIOIS</creatorcontrib><title>New spirotricyclic derivatives and their use as phosphodiesterase-7-inhibitors</title><description>本发明提供了属于PDE7抑制剂的具有下列通式(I)、(II)和(III)的化合物及其制备方法及其在治疗与采用PDE7抑制剂的疗法相关的疾病中的应用，其中X#-[1]、X#-[2]、X#-[3]、X#-[4]、X、Y、Z、A和Z#+[1]如本说明书中所定义。
The invention provides compounds which are PDE7 inhibitors, having the following formula (I), (II) and (III), in which X 1 , X 2 , X 3 , X 4 , X, Y, Z, A and Z 1 are as defined in the description, methods for preparing them and their use for the treatment of disorders for which therapy by a PDE7 inhibitor is relevant.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFyrEKwjAURuEsDqI-g_cFMrQK2lGK4pTJvcTkl14oSbg3Vnx7HdwdDt9ylsY5vEgLS67C4R0mDhQhPPvKM5R8ilRHsNBTQV6pjFm_RYZWiFfYg-U08p1rFl2bxcNPis3Pldlezrf-alHyAC0-IKEOvWv23bFt2tPu__EBna02cA</recordid><startdate>20040519</startdate><enddate>20040519</enddate><creator>P. BERNARDELLI</creator><creator>P. DUCROT</creator><creator>E. LORTHIOIS</creator><scope>EVB</scope></search><sort><creationdate>20040519</creationdate><title>New spirotricyclic derivatives and their use as phosphodiesterase-7-inhibitors</title><author>P. BERNARDELLI ; P. DUCROT ; E. LORTHIOIS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN1498212A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2004</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>P. BERNARDELLI</creatorcontrib><creatorcontrib>P. DUCROT</creatorcontrib><creatorcontrib>E. LORTHIOIS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>P. BERNARDELLI</au><au>P. DUCROT</au><au>E. LORTHIOIS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>New spirotricyclic derivatives and their use as phosphodiesterase-7-inhibitors</title><date>2004-05-19</date><risdate>2004</risdate><abstract>本发明提供了属于PDE7抑制剂的具有下列通式(I)、(II)和(III)的化合物及其制备方法及其在治疗与采用PDE7抑制剂的疗法相关的疾病中的应用，其中X#-[1]、X#-[2]、X#-[3]、X#-[4]、X、Y、Z、A和Z#+[1]如本说明书中所定义。
The invention provides compounds which are PDE7 inhibitors, having the following formula (I), (II) and (III), in which X 1 , X 2 , X 3 , X 4 , X, Y, Z, A and Z 1 are as defined in the description, methods for preparing them and their use for the treatment of disorders for which therapy by a PDE7 inhibitor is relevant.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | New spirotricyclic derivatives and their use as phosphodiesterase-7-inhibitors |
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