Antiacid and laxative tablets
一种抗酸・缓泻用片剂,以氧化镁粒子为有效成分,该片剂的特征在于:(i)其中所含的氧化镁粒子用激光衍射散射法测定得到的平均2次粒径是0.5~10μm,(ii)其中所含的氧化镁粒子的含量是88重量%以上,(iii)确认实质上没有发黑和压片斑,且(iv)崩解时间为10秒以下。本发明的抗酸・缓泻用片剂是氧化镁粒子的含量高,崩解时间短且实质上不存在压片障碍、发黑、压片斑,适于口服给药的抗酸・缓泻用含氧化镁粒子的片剂。 An antacid and laxative tablet comprising magnesium oxide particles as an effective component,...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | 一种抗酸・缓泻用片剂,以氧化镁粒子为有效成分,该片剂的特征在于:(i)其中所含的氧化镁粒子用激光衍射散射法测定得到的平均2次粒径是0.5~10μm,(ii)其中所含的氧化镁粒子的含量是88重量%以上,(iii)确认实质上没有发黑和压片斑,且(iv)崩解时间为10秒以下。本发明的抗酸・缓泻用片剂是氧化镁粒子的含量高,崩解时间短且实质上不存在压片障碍、发黑、压片斑,适于口服给药的抗酸・缓泻用含氧化镁粒子的片剂。
An antacid and laxative tablet comprising magnesium oxide particles as an effective component, wherein (i) the magnesium oxide particles contained in the tablet have an average secondary particle diameter measured by a laser diffraction scattering method of 0.5 to 10 mu m, (ii) the content of magnesium oxide particles in the tablet is 88 wt% or more, (iii) the tablet does not become blackish and has substantially no tableting spot, and (iv) the disintegration time is 10 sec or less. The antacid and laxative tablet of the present invention has a high content of magnesium oxide particles, a short disintegration time, does not become blackish, has no tablet trouble and no tableting spot and is suitably administered orally. |
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