Crystal form of 1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl] piperazine hydrochloride

本发明涉及1-[6-氯-5-(三氟甲基)-2-吡啶基]哌嗪盐酸盐(Org12962)的晶形A和B，涉及制备这些晶形的方法，还涉及含有晶形B的药物组合物。 The invention relates to crystal forms A and B of 1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazine hydrochloride (Org 12962), to methods for the preparation of those crystal forms and to pharmaceutical compositions co...

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Hauptverfasser:	P. CARLIER, P.J.C.M. HOOF VAN, J.C.J. MUYRERS
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	本发明涉及1-[6-氯-5-(三氟甲基)-2-吡啶基]哌嗪盐酸盐(Org12962)的晶形A和B，涉及制备这些晶形的方法，还涉及含有晶形B的药物组合物。 The invention relates to crystal forms A and B of 1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazine hydrochloride (Org 12962), to methods for the preparation of those crystal forms and to pharmaceutical compositions comprising crystal form B.