Method for preparing biomolecule chip flat-plate with hydrophilic and lipophilic area
A method for manufacturing an array plate for biomolecules and a method for manufacturing a biochip using this array plate are provided. The array plate manufacturing method includes: (a) coating a surface of a substrate (1) with a hydrophobic material to form a hydrophobic layer (3); (b) etching th...
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Zusammenfassung: | A method for manufacturing an array plate for biomolecules and a method for manufacturing a biochip using this array plate are provided. The array plate manufacturing method includes: (a) coating a surface of a substrate (1) with a hydrophobic material to form a hydrophobic layer (3); (b) etching the hydrophobic layer through an etch mask (4) placed thereon to form a hydrophilic binding site (5); (c) removing the remaining etch mask; and (d) processing the remaining region of the hydrophobic layer (3) to recover its original hydrophobic properties. The biochip manufacturing method includes processing the surface of the hydrophilic binding site (5) of an array plate manufactured using the method, and applying a solution containing biomolecules to the surface of the hydrophilic binding site. |
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