Substituted imidazole neuropeptide YY5 receptor antagonists

Compounds of the formula Ior a pharmaceutically acceptable salt, solvate or N-oxide thereof, wherein X is =CH- or =N-; Y is H, halogen, trihaloalkyl, alkyl, alkenyl, cycloalkyl, cycloalkyl, SH, -S-alkyl, or -CN. R is alkyl, -CF3 , cycloalkyl, heterocycloalkyl, heterocycloalkyl-alkyl, heteroarylalky...

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Bibliographische Detailangaben
Hauptverfasser:	A.W. STAMFORD, C.D. BOYLE, HUANG YING
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of the formula Ior a pharmaceutically acceptable salt, solvate or N-oxide thereof, wherein X is =CH- or =N-; Y is H, halogen, trihaloalkyl, alkyl, alkenyl, cycloalkyl, cycloalkyl, SH, -S-alkyl, or -CN. R is alkyl, -CF3 , cycloalkyl, heterocycloalkyl, heterocycloalkyl-alkyl, heteroarylalky or adamantyl, or optionally substituted phenyl, phenoxyalkyl, phenylthioalkyl, pyridyl, thienyl, thiazolyl, pyrazinyl, 1,2,5,6-tetrahydropyridine or wherein R