Amine and amide derivatives as ligands for neuropeptide YY5 receptor usefu in treatment of obesity and other disorders

Amine and amide derivatives as ligands for neuropeptide YY5 receptor usefu in treatment of obesity and other disorders

Amine and amide derivatives of formula (A) which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing amines and amides of formula (A) as the active ingredient are described. The amines and amides of formula (A) are useful in the tr...

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Bibliographische Detailangaben
Hauptverfasser: S.L. DAX, M. YOUNGMAN, J. MCNALLY
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Amine and amide derivatives of formula (A) which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing amines and amides of formula (A) as the active ingredient are described. The amines and amides of formula (A) are useful in the treatment of disorders and diseases associated with NPY receptor subtype Y5.