Breeding of hepatitis A virus Chinese strain and attenuated strain and its complementary DNA sequence

The present invention relates to hepatitis A virus Chinese strain and attenuated strain separation and cultivation and their complementary DNA sequence, in particular, it relates to separation and purification of hepatitis A virus Chinese strain, cultivation of series attenuated strain and its uniqu...

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Bibliographische Detailangaben
Hauptverfasser:	YONG CHEN, JIANGSEN MAO, SHAO'AI CHAI
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to hepatitis A virus Chinese strain and attenuated strain separation and cultivation and their complementary DNA sequence, in particular, it relates to separation and purification of hepatitis A virus Chinese strain, cultivation of series attenuated strain and its unique cDNA sequence. Said series cDNA series can provide basic material for further understanding genetic property and genetic stability of hepatitis A virus strain and expounding molecular mechanism of HAV attenuation, and can create condition for developing novel hepatitis A vaccine which can be quickly grown and possesses high titre and high antigenicity and can provide scientific basis for developing gene engineering polypeptide vaccine.