Pyrazine compounds

A compound of formula (I) wherein R1 is phenyl substituted by one or more halogen atoms; R2 is -NH2; R3 is -NH2 or hydrogen; R4 is -CXNRaRb, -CXNH-(CH2)y-NRaRb; wherein X is =O or =S; y is an integer zero, 1 or 2; Ra and Rb, which may be the same or different, are selected from hydrogen and C1-4 alk...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	M.P. HEALY, B. COX, D. WILD
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A compound of formula (I) wherein R1 is phenyl substituted by one or more halogen atoms; R2 is -NH2; R3 is -NH2 or hydrogen; R4 is -CXNRaRb, -CXNH-(CH2)y-NRaRb; wherein X is =O or =S; y is an integer zero, 1 or 2; Ra and Rb, which may be the same or different, are selected from hydrogen and C1-4 alkyl or together with the nitrogen atom to which they are attached form a saturated 5- or 6-membered heterocycle containing one or two nitrogen heteroatoms, which heterocycle can be further substituted with one or more C1-4 alkyl groups; and pharmaceutically acceptable derivatives thereof.