Sustained-release tablet comprising reboxetine

A sustained - release pharmaceutical composition in a form of an orally deliverable tablet comprising an active pharmaceutical agent having solubility not less than about 10mg/ml, dispersed in a matrix comprising a hydrophilic polymer and a starch having a tensile strength of at least about 0.15kNcm...

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Bibliographische Detailangaben
1. Verfasser: AMIDON GREGORY E.,GANORKAR LOKSIDH D.,REO JOSEPH P.,SKOUG CONNIE J.,HEIMLICH JOHM M.,NOACK ROBERT M.,MARTINO ALICE C.,LEE ERNEST J
Format: Patent
Sprache:eng
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Zusammenfassung:A sustained - release pharmaceutical composition in a form of an orally deliverable tablet comprising an active pharmaceutical agent having solubility not less than about 10mg/ml, dispersed in a matrix comprising a hydrophilic polymer and a starch having a tensile strength of at least about 0.15kNcm -2 at a solid fraction representative of the tablet.