Pyrrolidine-2-carboxylic acid hydrozide derivatives for use as metalloprotease inhibitors

The present invention relates to a pyrrolidine compound and pharmaceutically acceptable esters and/or salts thereof. The compounds are useful as inhibitors of metalloproteases, e.g. zinc proteases, particularly zinc hydrolases, and which are effective in treating disease states are associated with v...

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Bibliographische Detailangaben
1. Verfasser: JOHANNES AEBI,HENRIETTA DEHMLOW,ERIC ARGIRIOS KITAS
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to a pyrrolidine compound and pharmaceutically acceptable esters and/or salts thereof. The compounds are useful as inhibitors of metalloproteases, e.g. zinc proteases, particularly zinc hydrolases, and which are effective in treating disease states are associated with vasoconstriction of increasing occurrences.