Anhydrous crystalline azido cytosine hemisulfate derivative

The present invention relates to the hemisulfate salt of 4-amino-1-((2r,3r,4s,5r)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1h-pyrimidin-2-one with improved stability and physical properties which facilitate manufacturing, handling and formulating I and polymorphic crystalline for...

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Bibliographische Detailangaben
1. Verfasser:	MARTIN JOSEPH ARMSTRONG,SARMA KESHAB,PRINCE ANTHONY,CONNOLLY TERRENCE JOSEPH
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The present invention relates to the hemisulfate salt of 4-amino-1-((2r,3r,4s,5r)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1h-pyrimidin-2-one with improved stability and physical properties which facilitate manufacturing, handling and formulating I and polymorphic crystalline forms thereof.