Novel oripavine derivative and its medical use

The present invention relates to oripavine derivatives of formula (I), wherein R is hydrogen or methyl, R is methyl, cyclopropyl methyl, cyclobutyl methyl or allyl, R is thiophenyl ethyl or cycloalkyl methyl where the cycloalkyl has 3 to 6 carbon atoms, or non-toxic pharmaceutically acceptable salts...

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Bibliographische Detailangaben
1. Verfasser: BOHUA,GONG ZHONG
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to oripavine derivatives of formula (I), wherein R is hydrogen or methyl, R is methyl, cyclopropyl methyl, cyclobutyl methyl or allyl, R is thiophenyl ethyl or cycloalkyl methyl where the cycloalkyl has 3 to 6 carbon atoms, or non-toxic pharmaceutically acceptable salts thereof. These compounds can be used for the preparation of analgesics or abstinence agents of opium habit-forming drugs.