Benzamidine derivatives and use thereof as medicaments with LTB4-antagonistic effect
Benzamidine derivatives of formula (I), and their salts, are new: A =O(2-4C alkylene)O or (1-3C alkylene)O; R1 = 1-6C alkyl or halo; R2 = H, 1-6C alkyl or halo; R3, R4 = H, 1-6C alkyl, 1-6C alkoxy, OH, CF3; or R3+R4 = part of a condensed benzene ring (which may be substituted by OH, 1-4C alkyl or 1-...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | ERNST-OTTO RENTH RALF ANDERSKEWITZ KURT SCHROMM |
| description | Benzamidine derivatives of formula (I), and their salts, are new: A =O(2-4C alkylene)O or (1-3C alkylene)O; R1 = 1-6C alkyl or halo; R2 = H, 1-6C alkyl or halo; R3, R4 = H, 1-6C alkyl, 1-6C alkoxy, OH, CF3; or R3+R4 = part of a condensed benzene ring (which may be substituted by OH, 1-4C alkyl or 1-4C alkoxy); R5 = H, aryl, preferably Ph, OPh, CR7R8, COPh or CH(OH) (where the Ph ring may be substituted by OH or 1-4C alkoxy), or C(O)NR9R10; R6 = H, 1-6C alkoxycarbonyl or 1-6C acyl; and R7-R10 = H or 1-8C alkyl. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN1230174A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN1230174A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN1230174A3</originalsourceid><addsrcrecordid>eNqFyjEKwkAQBdA0FqKewblAwBjB2gTFQqzSh2H3rxkwk5AZI3h6G3ur17xl1lTQD_cSRUERk8zsMsOINdLLQN5hwpCIjXpECdxD3egt3tGtqQ45q_NjUDGXQEgJwdfZIvHTsPm5yraXc1Nfc4xDCxs5QOFtfS_25a44Hk7l__EFsZ03wg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Benzamidine derivatives and use thereof as medicaments with LTB4-antagonistic effect</title><source>esp@cenet</source><creator>ERNST-OTTO RENTH ; RALF ANDERSKEWITZ ; KURT SCHROMM</creator><creatorcontrib>ERNST-OTTO RENTH ; RALF ANDERSKEWITZ ; KURT SCHROMM</creatorcontrib><description>Benzamidine derivatives of formula (I), and their salts, are new: A =O(2-4C alkylene)O or (1-3C alkylene)O; R1 = 1-6C alkyl or halo; R2 = H, 1-6C alkyl or halo; R3, R4 = H, 1-6C alkyl, 1-6C alkoxy, OH, CF3; or R3+R4 = part of a condensed benzene ring (which may be substituted by OH, 1-4C alkyl or 1-4C alkoxy); R5 = H, aryl, preferably Ph, OPh, CR7R8, COPh or CH(OH) (where the Ph ring may be substituted by OH or 1-4C alkoxy), or C(O)NR9R10; R6 = H, 1-6C alkoxycarbonyl or 1-6C acyl; and R7-R10 = H or 1-8C alkyl.</description><edition>6</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; APPARATUS THEREFOR ; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; CHEMISTRY ; GENERAL METHODS OF ORGANIC CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990929&DB=EPODOC&CC=CN&NR=1230174A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19990929&DB=EPODOC&CC=CN&NR=1230174A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ERNST-OTTO RENTH</creatorcontrib><creatorcontrib>RALF ANDERSKEWITZ</creatorcontrib><creatorcontrib>KURT SCHROMM</creatorcontrib><title>Benzamidine derivatives and use thereof as medicaments with LTB4-antagonistic effect</title><description>Benzamidine derivatives of formula (I), and their salts, are new: A =O(2-4C alkylene)O or (1-3C alkylene)O; R1 = 1-6C alkyl or halo; R2 = H, 1-6C alkyl or halo; R3, R4 = H, 1-6C alkyl, 1-6C alkoxy, OH, CF3; or R3+R4 = part of a condensed benzene ring (which may be substituted by OH, 1-4C alkyl or 1-4C alkoxy); R5 = H, aryl, preferably Ph, OPh, CR7R8, COPh or CH(OH) (where the Ph ring may be substituted by OH or 1-4C alkoxy), or C(O)NR9R10; R6 = H, 1-6C alkoxycarbonyl or 1-6C acyl; and R7-R10 = H or 1-8C alkyl.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>APPARATUS THEREFOR</subject><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>GENERAL METHODS OF ORGANIC CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1999</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFyjEKwkAQBdA0FqKewblAwBjB2gTFQqzSh2H3rxkwk5AZI3h6G3ur17xl1lTQD_cSRUERk8zsMsOINdLLQN5hwpCIjXpECdxD3egt3tGtqQ45q_NjUDGXQEgJwdfZIvHTsPm5yraXc1Nfc4xDCxs5QOFtfS_25a44Hk7l__EFsZ03wg</recordid><startdate>19990929</startdate><enddate>19990929</enddate><creator>ERNST-OTTO RENTH</creator><creator>RALF ANDERSKEWITZ</creator><creator>KURT SCHROMM</creator><scope>EVB</scope></search><sort><creationdate>19990929</creationdate><title>Benzamidine derivatives and use thereof as medicaments with LTB4-antagonistic effect</title><author>ERNST-OTTO RENTH ; RALF ANDERSKEWITZ ; KURT SCHROMM</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN1230174A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1999</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>APPARATUS THEREFOR</topic><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>GENERAL METHODS OF ORGANIC CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>ERNST-OTTO RENTH</creatorcontrib><creatorcontrib>RALF ANDERSKEWITZ</creatorcontrib><creatorcontrib>KURT SCHROMM</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ERNST-OTTO RENTH</au><au>RALF ANDERSKEWITZ</au><au>KURT SCHROMM</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Benzamidine derivatives and use thereof as medicaments with LTB4-antagonistic effect</title><date>1999-09-29</date><risdate>1999</risdate><abstract>Benzamidine derivatives of formula (I), and their salts, are new: A =O(2-4C alkylene)O or (1-3C alkylene)O; R1 = 1-6C alkyl or halo; R2 = H, 1-6C alkyl or halo; R3, R4 = H, 1-6C alkyl, 1-6C alkoxy, OH, CF3; or R3+R4 = part of a condensed benzene ring (which may be substituted by OH, 1-4C alkyl or 1-4C alkoxy); R5 = H, aryl, preferably Ph, OPh, CR7R8, COPh or CH(OH) (where the Ph ring may be substituted by OH or 1-4C alkoxy), or C(O)NR9R10; R6 = H, 1-6C alkoxycarbonyl or 1-6C acyl; and R7-R10 = H or 1-8C alkyl.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_CN1230174A |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR RELEVANT APPARATUS TRANSPORTING |
| title | Benzamidine derivatives and use thereof as medicaments with LTB4-antagonistic effect |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T14%3A10%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ERNST-OTTO%20RENTH&rft.date=1999-09-29&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN1230174A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |