2,2-disubstituted 1,3-dioxolanes as antitussive atents

(±) 3-(4-Phenyl-1-piperazinyl)-1,2-propanediol cyclic acetals, a process for the optical resolution thereof and their use as intermediates for the preparation of (-) 3-(4-phenyl-1-piperazinyl)-1,2-propanediol (levodropropizine) and salts thereof are described herein.

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Bibliographische Detailangaben
Hauptverfasser: M.C. CESTA, R. CURTI, M. ALLEGRETTI
Format: Patent
Sprache:eng
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Zusammenfassung:(±) 3-(4-Phenyl-1-piperazinyl)-1,2-propanediol cyclic acetals, a process for the optical resolution thereof and their use as intermediates for the preparation of (-) 3-(4-phenyl-1-piperazinyl)-1,2-propanediol (levodropropizine) and salts thereof are described herein.