Layered material having mucoadhesive properties, and patch and microneedle patch comprising same

The invention provides a layered material with mucosal adhesion, which comprises a modified acrylic polymer and hydroxypropyl methylcellulose, the weight ratio of the modified acrylic polymer to the hydroxypropyl methylcellulose is 1: 4 to 4: 1, and the thickness of the layered material is 0.0001 mm to 100 mm. The layered material disclosed by the invention has mucous membrane adhesion, can be prepared into a patch or a microneedle patch, assists the patch or the microneedle patch in fixation, and is beneficial to drug sustained release. The invention also provides a patch comprising the layered material. In addition, the invention also provides a microneedle patch which comprises a microneedle layer, a substrate layer and a back layer, the back layer comprises the layered material, the microneedle patch can be fixed favorably, and the microneedle patch is suitable for being used by a focus on a mucosa. 本发明提供一种具有粘膜粘附性的层状材料，其包含一改性丙烯酸聚合物和羟丙甲纤维素，其中该改性丙烯酸聚合物和羟丙甲纤维素的重量比为1：4至4：1，且该层状材料的厚度为0.0001毫米至100毫米。本发明的层状材料具有粘