Drug-loaded thermochromic soluble microneedle for moxibustion treatment as well as preparation and application of drug-loaded thermochromic soluble microneedle

The invention provides a drug-loaded thermochromic soluble microneedle for moxibustion treatment and preparation and application thereof. A preparation method of the drug-loaded thermochromic soluble microneedle comprises the following steps: (1) preparing a microneedle mold; (2) preparing a soluble polymer polyvinylpyrrolidone solution containing a thermochromic dye; (3) preparing a tanshinone-loaded hyaluronic acid solution; and (4) filling the tanshinone-loaded hyaluronic acid solution into a needle tip of a mold, then filling the backing part with a soluble polymer solution containing a thermochromic dye, drying, and stripping the mold to obtain the drug-loaded thermochromic soluble microneedle. The tanshinone-loaded hyaluronic acid solution serves as a needle tip part and is used for efficiently delivering drugs, and the soluble polymer solution containing the thermochromic dye serves as a backing material and can monitor the temperature of the skin surface of a moxibustion acupoint. By combining the the