Fluorescent composite molecular probe and application thereof

The invention relates to the field of biological detection, in particular to a fluorescent composite molecular probe and application thereof. The fluorescent composite molecular probe provided by the invention comprises one or more Forster resonance energy transfer (FRET) fluorescent units, and the...

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Bibliographische Detailangaben
Hauptverfasser:	AI GONGLI, ZOU YAN, WU FAN, PAN CHENGDA, HU CHUNRUI, WANG SHU, CHEN CHANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ADHESIVES BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA DYES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS MUTATION OR GENETIC ENGINEERING NATURAL RESINS PAINTS PHYSICS POLISHES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to the field of biological detection, in particular to a fluorescent composite molecular probe and application thereof. The fluorescent composite molecular probe provided by the invention comprises one or more Forster resonance energy transfer (FRET) fluorescent units, and the FRET fluorescent units comprise donor molecules and acceptor molecules with unequal numbers. The fluorescent composite molecular probe provided by the invention has the characteristics of high FRET (Fluorescence Resonance Energy Transfer) efficiency, stable luminescence, differentiation, multi-stage, specificity, easiness in preparation, high biological reaction compatibility and low cost under a single excitation wavelength and a single emission wavelength, and is suitable for detecting biomacromolecules (DNA (Deoxyribose Nucleic Acid), RNA (Ribose Nucleic Acid), MRI (Metal Oxide Semiconductor), MRI (Metal Oxide Semiconductor) and MRI). The invention can be applied to biological and medical fields such as protein