Transdermal microneedle patch with photothermal effect as well as preparation method and application of transdermal microneedle patch

The invention provides a transdermal microneedle patch with a photothermal effect as well as a preparation method and application of the transdermal microneedle patch, and belongs to the technical field of medical materials. According to the transdermal microneedle patch provided by the invention, the Fe3O4 nanoparticles serving as a photothermal conversion agent are encapsulated in the tip of the microneedle patch, so that the photothermal conversion efficiency is high, and the temperature is controllable. The transdermal microneedle patch provided by the invention is strong in skin penetrating power and convenient to operate, can cooperate with photothermal therapy, has the unique advantages of higher selectivity, minimum invasiveness and side effects and capability of realizing local controllable mild thermal therapy, and shows very wide application prospects in clinical disease treatment. 本发明提供了一种具有光热效应的透皮微针贴片及其制备方法和应用，属于医用材料技术领域。本发明提供的透皮微针贴片将光热转换剂Fe3O4纳米粒子封装于微针贴片针尖内，光热转换效率高，温度可控。本发明提供的透皮微针贴片皮肤穿透能力强，操作便捷，