Application of anti-SSTR3 autoantibody detection reagent in diagnosis of nervous system autoimmune diseases

The invention belongs to the technical field of biological medicines, and particularly relates to application of a reagent for detecting an anti-SSTR3 autoantibody in diagnosis of nervous system autoimmune diseases. The serum of a patient suffering from the nervous system autoimmune disease is compa...

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Hauptverfasser: SUN MINMIN, REN NI, YAN YAPING, ZHANG ZHEWEI, HUANG XIULI, CHAI SHANSHAN, LIU KEXIN, SU ZHAOPENG, XI QIAN, LIU HUI, LI KE, GUO JUN, HAO WENBIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of biological medicines, and particularly relates to application of a reagent for detecting an anti-SSTR3 autoantibody in diagnosis of nervous system autoimmune diseases. The serum of a patient suffering from the nervous system autoimmune disease is compared with the serum of a healthy person, and a signal existing in the serum of the patient but not existing in the serum of the healthy person is found: an autoantibody of an SSTR3 antigen is recognized, and the serum of the patient suffering from the nervous system autoimmune disease and the serum of the healthy person are detected; the invention finds that healthy people are negative in anti-SSTR3 autoantibody and part of nervous system autoimmune disease patients are positive in anti-SSTR3 autoantibody, and determines that the anti-SSTR3 autoantibody can be used as a marker for diagnosing the nervous system autoimmune disease, thereby enriching biomarkers for identifying the nervous system autoimmune disease and