Azimine hydrochloride tablet and preparation method thereof

The invention discloses an Azimine hydrochloride tablet and a preparation method thereof, and belongs to the technical field of medicines.The Azimine hydrochloride tablet is composed of an Azimine hydrochloride tablet core and a film coating, comprising 20 to 45 parts of Azimine hydrochloride, 40 to...

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Bibliographische Detailangaben
Hauptverfasser: MA LI, WU PANPAN, XU NING, NAKADATSU
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses an Azimine hydrochloride tablet and a preparation method thereof, and belongs to the technical field of medicines.The Azimine hydrochloride tablet is composed of an Azimine hydrochloride tablet core and a film coating, comprising 20 to 45 parts of Azimine hydrochloride, 40 to 90 parts of lactose monohydrate, 20 to 60 parts of microcrystalline cellulose, 2 to 10 parts of hydroxy propyl cellulose, 2 to 8 parts of croscarmellose sodium, 0.2 to 1.2 parts of colloidal silicon dioxide and 0.5 to 2.5 parts of magnesium stearate. The film coating comprises 70wt% of polyvinyl alcohol, 3wt% of titanium dioxide, 2wt% of talcum powder, 10wt% of lecithin, 10wt% of xanthan gum and 5wt% of a coloring agent. By optimizing the proportion of the components, the prepared azilnimil hydrochloride tablet is good in dissolution rate, good in unit uniformity of central control dosage, and good in indexes such as content uniformity. 本发明公开了一种盐酸阿西米尼片及其制备方法,属于医药技术领域,所述盐酸阿西米尼片由盐酸阿西米尼片芯和薄膜包衣组成,盐酸阿西米尼片芯,包括盐酸阿西米尼20-4