Preparation process of mulberry leaf source functional substance with hypoglycemic activity

The invention discloses a preparation process of a non-alkaloid hypoglycemic active component MPP from mulberry leaves, which comprises the following steps: crushing mulberry leaves, and then carrying out water extraction and alcohol precipitation, concentration, solvent dissolution, cation exchange resin purification, macroporous resin purification and freeze drying to separate and obtain the non-alkaloid component MPP with hypoglycemic activity. The content of alkaloid 1-deoxynojirimycin detected by liquid chromatography is less than 0.5%, and the content of polyphenol (in terms of gallic acid) detected by a folin-phenol method is not less than 60%. Compared with similar products, the product disclosed by the invention not only has outstanding alpha-glycosidase activity, but also can scavenge free radicals to reduce cellular oxidative stress caused by high glucose, and alleviate insulin resistance by inhibiting hepatic cell gluconeogenesis, and has an application prospect in adjuvant therapy of diabetes mel