Temperature-sensitive hydrogel, canine parvovirus CPV-2c subtype virus-like particle temperature-sensitive gel vaccine as well as preparation method and application thereof
The invention discloses temperature-sensitive hydrogel, a canine parvovirus-like particle (CPV-2c) subtype virus-like particle temperature-sensitive gel vaccine as well as a preparation method and application of the canine parvovirus-like particle temperature-sensitive gel vaccine and relates to the...
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| creator | QIAN JING XIA XINGXIA WANG YONGSHAN ZHU YUMEI JIANG SHANXIANG TAN YEPING BI ZHENWEI MO FEI |
| description | The invention discloses temperature-sensitive hydrogel, a canine parvovirus-like particle (CPV-2c) subtype virus-like particle temperature-sensitive gel vaccine as well as a preparation method and application of the canine parvovirus-like particle temperature-sensitive gel vaccine and relates to the field of vaccines. 2 to 5 percent of poloxamer P188; and 0.2%-0.5% of carboxymethyl cellulose HPMC. The temperature-sensitive hydrogel can be used as a vaccine vector to prepare a canine parvovirus (CPV)-2c subtype virus-like particle temperature-sensitive gel vaccine. According to the invention, a CPV current epidemic virulent strain JSLYG-18 is used as a vaccine immune template, and the specificity is strong. The prepared canine parvovirus-like particle temperature-sensitive gel vaccine is high in immunogenicity, long in immune effect lasting time, high in antibody titer and excellent in anti-CPV biological activity. The temperature-sensitive hydrogel is used as a vaccine carrier, so that the vaccine is high in |
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The temperature-sensitive hydrogel can be used as a vaccine vector to prepare a canine parvovirus (CPV)-2c subtype virus-like particle temperature-sensitive gel vaccine. According to the invention, a CPV current epidemic virulent strain JSLYG-18 is used as a vaccine immune template, and the specificity is strong. The prepared canine parvovirus-like particle temperature-sensitive gel vaccine is high in immunogenicity, long in immune effect lasting time, high in antibody titer and excellent in anti-CPV biological activity. 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The temperature-sensitive hydrogel can be used as a vaccine vector to prepare a canine parvovirus (CPV)-2c subtype virus-like particle temperature-sensitive gel vaccine. According to the invention, a CPV current epidemic virulent strain JSLYG-18 is used as a vaccine immune template, and the specificity is strong. The prepared canine parvovirus-like particle temperature-sensitive gel vaccine is high in immunogenicity, long in immune effect lasting time, high in antibody titer and excellent in anti-CPV biological activity. The temperature-sensitive hydrogel is used as a vaccine carrier, so that the vaccine is high in</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | Temperature-sensitive hydrogel, canine parvovirus CPV-2c subtype virus-like particle temperature-sensitive gel vaccine as well as preparation method and application thereof |
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