S/N co-doped carbon-based nano enzyme (at) DOX composite material as well as preparation method and application thereof

The invention discloses an S/N co-doped carbon-based nano enzyme (at) DOX composite material as well as a preparation method and application thereof. Silicon dioxide is used as a hard template, zinc chloride is used as a pore-forming agent, glucosamine hydrochloride is used as an N source and a C source, thiourea is used as an S source, S and N are simultaneously doped in a carbon skeleton through one-pot high-temperature pyrolysis annealing, and finally the hard template is removed by hydrofluoric acid, so that the S/N co-doped carbon-based nano-enzyme SNC with a layered porous structure is obtained. Then, after PEGylation modification, an anti-cancer drug doxorubicin (DOX) is conveniently loaded by utilizing a layered porous structure of the S/N co-doped carbon-based nano enzyme (at) DOX composite material to obtain the S/N co-doped carbon-based nano enzyme (at) DOX composite material. The composite material has a remarkable photothermal effect and tumor microenvironment response enzyme-like catalytic activ