Treatment of cardiopulmonary conditions

The present invention relates to (5S)-{[2-(4-carboxyphenyl) ethyl] [2-(2-{[3-chloro-4 '-(trifluoromethyl) biphenyl-4-yl] methoxy} phenyl) ethyl]-amino}-5, 6, 7, 8-tetrahydroquinoline-2-carboxylic acid of formula (I), preferably in the form of one of its salts or solvates or hydrates, the presen...

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Bibliographische Detailangaben
Hauptverfasser:	RICHTER ANDREAS, FAY, PAUL, FU RBER, HORST, VITRE CYRIL, LANG DIETER, BECK, GERHARD, BOTT CHARLES, DIETZ LISA, TREVISI ISABELLE, OLENIK BRITTA, EGGER JOHANNES, WEIMANN, G ¨ 1 NTER, ROESLER BURKARD, BECKER-PELSTER, EVA, M, JUNG DETLEF, SCHIRMER HEIKO, TINEL HANNA, HAHN MARTIN, SALEH SAMEH, KEIL BIRGIT, PARI MARCO, NAGELSCHMITZ, J ¨ 1 RGEN, WARD DONALD, MUNDRY THOMAS
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to (5S)-{[2-(4-carboxyphenyl) ethyl] [2-(2-{[3-chloro-4 '-(trifluoromethyl) biphenyl-4-yl] methoxy} phenyl) ethyl]-amino}-5, 6, 7, 8-tetrahydroquinoline-2-carboxylic acid of formula (I), preferably in the form of one of its salts or solvates or hydrates, the present invention relates to (5S)-{[2-(4-carboxyphenyl) ethyl] [2-(2-{[3-chloro-4 '-(trifluoromethyl) biphenyl-4-yl] methoxy} phenyl) ethyl]-amino}-5, 6, 7, 8-tetrahydro-2H-1, 2, 3, 4-tetrahydro-2H-1, 2, 3-tetrahydro-2H-1, 2, 3-tetrahydro-2H-1, 2, 3-tetrahydro-2H-1, 2, 3-tetrahydro-2H-1, 2, 3-tetrahydro-2H- (5S)-{[2-(4-carboxyphenyl) ethyl] [2-(2-{[3-chloro-4 '-(trifluoromethyl) biphenyl-4-yl] methoxy} phenyl) ethyl]-amino}-5, 6, 7, 8-tetrahydroquinoline-2-carboxylic acid of formula (I-M-II) in the form of a monohydrate (II) in the treatment of cardiopulmonary and pulmonary conditions, such as cardiovascular and pulmonary conditions. The present invention relates to the use in the inhalation treatment of pulmonary hypertensio