Synthesis of Bruton's tyrosine kinase inhibitor

The present invention relates to a process for the synthesis of a compound of formula (I) wherein the R group is as defined herein, # imgabs0 # and to a process for the synthesis of a compound of formula (II): # imgabs1 # some aspects of the present disclosure relate to the conversion of a compound of formula (II) to the P form of the compound. 本发明涉及合成式(I)的化合物的方法，其中R基团如本文所定义，#imgabs0#并且涉及合成式(II)的化合物的方法：#imgabs1#本公开的一些方面涉及将式(II)的化合物转化成该化合物的P形式。