Pharmaceutical formulation

The present invention relates to a pharmaceutical formulation comprising an active pharmaceutical ingredient (3S, 3S, 3S ', 3S', 3S ', 3S', 3S ', 3S', 3S ', 3S', 3S ', 3S' The present invention relates to a pharmaceutical composition comprising a pha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LOWALEKA ROBERT, GURURAJAN BALAJI, SAVAI, TAMER, REYNAUD ERIC, PAWAR YOGESH, ROGGE, VOLKER
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention relates to a pharmaceutical formulation comprising an active pharmaceutical ingredient (3S, 3S, 3S ', 3S', 3S ', 3S', 3S ', 3S', 3S ', 3S', 3S ', 3S' The present invention relates to a pharmaceutical composition comprising a pharmaceutically acceptable salt of (4S)-8-(6-amino-5-((2-amino-3-chloropyridin-4-yl) thio) pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro [4.5] decane-4-amine, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable excipient, the pharmaceutical formulation is made by a process including wet granulation, direct compression or in particular rolling. 本发明涉及一种药物配制品以及本文披露的相关的本发明的方面,该药物配制品包含活性药物成分(3S,4S)-8-(6-氨基-5-((2-氨基-3-氯吡啶-4-基)硫代)吡嗪-2-基)-3-甲基-2-氧杂-8-氮杂螺[4.5]癸烷-4-胺或其药学上可接受的盐和至少一种药学上可接受的赋形剂,其中特别地,该药物配制品通过包括湿法造粒、直接压缩或尤其是辊压的工艺制成。