Macrocyclic btk inhibitors

The present invention relates to macrocyclic compounds useful as kinase inhibitors, in particular as BTK (Bruton's Tyrosine Kinase) inhibitors, and compositions containing said compounds. Furthermore, the present invention provides methods of making the disclosed compounds and methods of using...

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Hauptverfasser: BUCHMANN RICHARD C, STRU MBERG, JAN, G, GROBEN YUVAL, DE MAN ADRIANUS PETRUS ANTONIUS, VU-PHAM, DUY, DE WIT JOERI JOHANNES PETRUS, VAN COTT, FRANK, M ¨ 1 LLER, MICHAEL, VAN GEMERT, SIMON, P., W, PRINSEN MARTINUS BERNARDUS WILHELMUS, SIMMONS-VAN RIEL WILLEM EDUARD, VAN MEEL, YURI, GERARDUS, THEODORUS, MULDER, WILHELMUS, R
Format: Patent
Sprache:chi ; eng
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