MODIFIED CELLS AND USES THEREOF

The present disclosure provides modified immune cells, proteins encoding PD-L1 variants, and polynucleotides encoding the same. Also provided are pharmaceutical compositions comprising them and methods of treating disease. 本公开提供了经修饰的免疫细胞、编码PD-L1变体的蛋白质和编码它们的多核苷酸。还提供了包含它们的药物组合物和治疗疾病的方法。...

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Hauptverfasser: SHI XIUJUAN, DU BING, TAN BINGHE, LIU MINGYAO, XI ZAIXI, ZHANG JIQIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present disclosure provides modified immune cells, proteins encoding PD-L1 variants, and polynucleotides encoding the same. Also provided are pharmaceutical compositions comprising them and methods of treating disease. 本公开提供了经修饰的免疫细胞、编码PD-L1变体的蛋白质和编码它们的多核苷酸。还提供了包含它们的药物组合物和治疗疾病的方法。