Novel CEST contrast agent for evaluating NO biological effect as well as preparation method and application of novel CEST contrast agent

The invention discloses a novel CEST contrast agent for evaluating NO biological effect, and a preparation method and application thereof. The molecular formula of the contrast agent disclosed by the invention is C12H34CuN10O13, and the molecular formula of the contrast agent disclosed by the invention is The contrast agent belongs to a monoclinic system, the cell parameters are as follows: # imgabs 0 # alpha = (90) degrees, beta = 92.108 (7) degrees, gamma = (90) degrees, and the cell volume # imgabs 1 #. The contrast agent provided by the invention has the advantages of cheap and easily available raw materials, mild reaction conditions, few synthesis steps and simple product treatment; the prepared novel CEST contrast agent can realize rapid and sensitive imaging and detection of NO release, and the detection signal is stable and is not interfered by external factors. 本发明公开了一种评估NO生物学效应的新型CEST造影剂及其制备方法和应用。本发明所述造影剂的分子式为：C12H34CuN10O13；属于单斜晶系，晶胞参数为：#imgabs0#α＝(90)°，β＝92.108(7)°，γ＝(90)°，晶胞体积#imgabs1#本发明所述造影剂制备原