Display panel and manufacturing method thereof

The invention relates to a display panel and a manufacturing method of the display panel. The display panel comprises a substrate and an isolation structure, a plurality of isolation openings are formed in the isolation structure at intervals, the isolation structure comprises an upper portion and a lower portion, the orthographic projection of the lower portion on the substrate is located in the orthographic projection of the upper portion on the substrate, and the isolation openings comprise the first isolation opening, the second isolation opening and the third isolation opening. In the first isolation opening, the distance between the orthographic projection edges of the upper part and the lower part on the substrate is D1; in the second isolation opening, the distance between the orthographic projection edges of the upper part and the lower part on the substrate is D2; in the third isolation opening, the distance between the orthographic projection edges of the upper part and the lower part on the substr