Gene regulatory region editing method based on artificial intelligence

The invention belongs to the field of bioinformatics, and particularly relates to a gene regulatory region editing method based on artificial intelligence. According to the method, an artificial intelligence algorithm is used for performing simulation mutation on a gene regulation and control region...

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Bibliographische Detailangaben
Hauptverfasser:	HU XUEHAI, JIN MINLIANG, QIU YANG, XU JIETING, LIU LIFEN, YAN JIANBING, WANG SHOUZHE, WU XIAOYU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CALCULATING CHEMISTRY COMPOSITIONS THEREOF COMPUTER SYSTEMS BASED ON SPECIFIC COMPUTATIONAL MODELS COMPUTING COUNTING CULTURE MEDIA ENZYMOLOGY INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention belongs to the field of bioinformatics, and particularly relates to a gene regulatory region editing method based on artificial intelligence. According to the method, an artificial intelligence algorithm is used for performing simulation mutation on a gene regulation and control region formed by a promoter, 5 '-UTR, 3'-UTR and a terminator to measure the influence of different gene editing schemes on gene expression, so that an accurate gene editing scheme is generated according to breeding requirements. 本发明属于生物信息学领域，具体涉及一种基于人工智能的基因调控区编辑方法。本发明使用人工智能算法对启动子、5'-UTR、3'-UTR、终止子构成的基因调控区进行模拟突变，以衡量不同基因编辑方案对基因表达的影响，从而根据育种需求生成精准的基因编辑方案。