Degradable antibacterial hydrogel and preparation method thereof

The invention discloses degradable antibacterial hydrogel and a preparation method thereof, and relates to the technical field of hydrogel. When the degradable antibacterial hydrogel is prepared, o-phenylenediamine and 3-nitropropionaldehyde are subjected to a reaction, and nitrobenzimidazole is prepared; reacting the nitrobenzimidazole with hydrogen to prepare aminobenzimidazole; the preparation method comprises the following steps: reacting hyaluronic acid with aminobenzimidazole to obtain modified hyaluronic acid; the preparation method comprises the following steps: preparing an emulsion from polypeptide and chitosan, and cross-linking with glutaraldehyde to prepare polypeptide-chitosan porous microspheres; enabling the polypeptide-chitosan porous microspheres to react with calcium chloride to prepare modified polypeptide-chitosan porous microspheres; the modified hyaluronic acid, the modified polypeptide-chitosan porous microspheres and hexamethylene diisocyanate are subjected to a reaction, and the degr