Nested microsphere hydrogel carrying double exosomes as well as preparation method and application of nested microsphere hydrogel

Nested microsphere hydrogel carrying double exosomes as well as preparation method and application of nested microsphere hydrogel

The invention is applicable to the technical field of tissue engineering, and provides a preparation method of nested microsphere hydrogel carrying double exosomes, and the preparation method comprises the following steps: preparing o-exos and exos; preparing a white porous foamed GelMA hydrogel pre...

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Hauptverfasser: LYU HUIXIN, ZHANG JIAMENG, CHEN JINGXIA, CHEN SHENG, ZHOU YANMIN, WANG YIHAN
Format: Patent
Sprache:chi ; eng
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CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
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creator LYU HUIXIN
ZHANG JIAMENG
CHEN JINGXIA
CHEN SHENG
ZHOU YANMIN
WANG YIHAN
description The invention is applicable to the technical field of tissue engineering, and provides a preparation method of nested microsphere hydrogel carrying double exosomes, and the preparation method comprises the following steps: preparing o-exos and exos; preparing a white porous foamed GelMA hydrogel precursor; the preparation method comprises the following steps: weighing Fibrinogen, dissolving the Fibrinogen in PBS (Phosphate Buffer Solution) containing o-exos, so as to obtain a Fibrinogen hydrogel precursor solution carrying the exosome, and carrying out photo-crosslinking polymerization, so as to obtain the Fibrinogen-exos microsphere hydrogel; the preparation method comprises the following steps: weighing a GelMA hydrogel precursor, dissolving the GelMA hydrogel precursor in PBS (Phosphate Buffer Solution) containing exos, fully and uniformly mixing the PBS containing exos with the Fibrinogeno-exos microsphere hydrogel, and carrying out photo-crosslinking polymerization, so as to obtain the GelMA exos-Fibrino
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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
title Nested microsphere hydrogel carrying double exosomes as well as preparation method and application of nested microsphere hydrogel
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