Application of oleuropein and analogues thereof in preparation of anti-coronavirus drugs

The invention discloses application of oleuropein and analogues thereof in preparation of anti-coronavirus drugs, and belongs to the technical field of medicines. Specifically disclosed are oleuropein and analogues thereof or pharmaceutically acceptable salts thereof, and solvates, enantiomers, diastereoisomers, tautomers of the oleuropein and analogues thereof or pharmaceutically acceptable salts thereof or mixtures thereof in any proportion. Comprising application of the racemic mixture in preparation of drugs for preventing and/or treating diseases caused by coronavirus. And the coronavirus is MERS-CoV (Mean Electrophoresis Research Standard CoV), SARS-CoV or SARS-CoV-2 (Sharpening The invention finds that the oleuropein and analogues thereof can play a role in resisting the coronavirus by inhibiting the activity of the 3CL protease of the coronavirus, and the oleuropein has the best inhibiting effect on the 3CL protease, so that the oleuropein and analogues thereof are a promising drug for treating diseas