Innovative biotechnological system for detection of cellular or molecular analytes

The present invention relates to a method for detecting a cellular or molecular analyte using two types of engineered bacteriophages: a "capture" bacteriophage (bait bacteriophage) and a "signal" bacteriophage (reporter bacteriophage). By the method, a target analyte can be selec...

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Bibliographische Detailangaben
Hauptverfasser: CALVARESI MADIO, DANIELI ALBERTO, PETROSINO, ANNABOLA, KONOCH, SABRINA, FAZIO, ENZA, DI GIOSCIA MATTEO, GUGLIELMINO, SALVATORE, PRODI LUCA
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention relates to a method for detecting a cellular or molecular analyte using two types of engineered bacteriophages: a "capture" bacteriophage (bait bacteriophage) and a "signal" bacteriophage (reporter bacteriophage). By the method, a target analyte can be selectively bound, thereby identifying the target analyte. 本发明涉及一种用于检测细胞或分子分析物的方法,所述方法利用两种类型的工程化噬菌体:"捕获"噬菌体(诱饵噬菌体)和"信号"噬菌体(报告噬菌体)。通过该方法,可以选择性地结合目标分析物,从而识别该目标分析物。